TOKYO DIRECTJapanese biotech skincare, shipped directly from Tokyo.Available from Japan. Delivered worldwide.

JAPANESE SCIENCE-LED SKINCARE

Skin, quietly
renewing

Science, refined for skin.

Global science and Japanese precision, translated into a refined daily ritual.
CELLshot begins with skin health and creates beauty designed to endure.

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01 — PHILOSOPHY

Science, refined
for skin

We look beyond surface beauty and stay with the skin’s long-term wellbeing—bridging scientific precision and Japanese craftsmanship into daily skincare.

01

Global Scientific
Perspective

Frontier insight translated with scientific discipline.
02

Japanese Precision
Craft

Designed, manufactured and quality-reviewed in Japan.
03

Daily Skin
Ritual

Advanced care shaped for consistent, comfortable use.

02 — THE CELLshot FAMILY

One system.
Every step.

From daily care to intensive rituals, every product follows one philosophy and works with the skin’s rhythm.

Biomembrane-infused targeted stem-cell extracellular vesicle freeze-dried serum product visualSTEP 1

1AgeCare ExoMask Pro

Biomembrane InfusionTargeted Stem-Cell EV Freeze-Dried Serum

A 45-minute intensive ritual with one freeze-dried extracellular-vesicle biomembrane and three infusion essences.View details
Dual-chamber flash-release targeted stem-cell extracellular vesicle serum product visualSTEP 2

2AgeCare ExoSerum Pro

Dual-Chamber Flash ReleaseTargeted Stem-Cell EV Serum

A dual-chamber freeze-dried extracellular-vesicle serum activated immediately before use.View details
Multi-action peptide serum product visualSTEP 3COMING SOON

3Multi-Action Serum

Multi-Action Peptide SerumAn Everyday AM & PM Classic

A new expression from CELLshot. Product details will be released progressively.View details

03 — SCIENCE / ORIGINAL INGREDIENT

We create the ingredient.
We design the product.

At the heart of CELLshot is a human endometrial stem-cell extracellular-vesicle ingredient developed by tiptop and carried through international and Japanese cosmetic nomenclature. The ingredient developer shapes the full journey—from preservation and packaging to formulation and manufacturing in Japan.

ORIGINAL INGREDIENTHuman Endometrial
Stem Cell Exosomes
INCI / MONO ID
39006
JCIA / 受付番号
22787
ヒト子宮内膜幹細胞エクソソーム

03 — SCIENCE

Protected until
the moment of use

Drawing on extracellular-vesicle research, CELLshot uses freeze-drying, separated phases and mixing immediately before use.

Freeze-dried
A powder-state design for preserving delicate ingredients
Freshly mixed
Two phases mix immediately before use, flash-releasing the freeze-dried extracellular vesicles
Made in Japan
Manufacturing and quality review in Japan
Read the science

04 — YOUR RITUAL

One system.
Designed to work together.

A shared core ingredient and design system connects morning-and-evening care, a freshly activated weekly bottle and a 45-minute intensive ritual—each step built to complement the next.

DAILYMorning & eveningWEEKLYOne fresh bottle45 MINIntensive care
Explore the ritual

05 — EVIDENCE & RESULTS

Remarkable results.
Rigorously measured.

The more remarkable the result, the more rigorous the measurement should be. SGS human efficacy evaluation uses multiple research-grade instruments, facial zones and metrics from 15 minutes through Day 28—and we disclose the conditions, instruments and methods behind the data.

Explore evidence and results
VISIA / VISIA-CR 功效测量设备视觉01

VISIA / VISIA-CR

A standardized imaging system widely used in skin research and efficacy evaluation, turning complex skin conditions into reproducible, research-grade visual records.

PRIMOS CR 功效测量设备视觉02

PRIMOS CR

Research-grade optical topography that reconstructs skin in high-resolution 3D and converts wrinkle count, depth, length, area and volume into publication-ready metrics.

Multiphoton Tomography 功效测量设备视觉03

Multiphoton Tomography

Advanced non-invasive optical tomography that looks beyond the surface and explores microscopic skin structure with a research-level field of view.

VISIA / VISIA-CR standardized imaging, PRIMOS CR 3D skin-surface measurement and exploratory multiphoton microscopy. The instruments do not recommend products; they independently and objectively measure human efficacy outcomes and record changes in the data.

06 — A MESSAGE

Frontier science.
Made for daily life.

“Global scientific resonance. Japanese precision. Eastern life intelligence.”

Our mission is to bring progress in life science beyond laboratories and innovative medicine—earlier, more broadly and into everyday life. CELLshot refines frontier insight through Japanese craftsmanship into skincare designed to be lived with.

Read our story
powered by tiptop

POWERED BY tiptop / TECHNOLOGY PLATFORM

From original ingredients to precision-made skincare

tiptop connects global scientific insight, original ingredient development, international nomenclature, quality design and precision manufacturing in Japan. Powered by tiptop, CELLshot translates that capability into skincare made for real rituals.

Explore the tiptop technology platform